Certificate of Analysis

 

Catalog Number: M2734
Product Name: GSK2606414
CAS Number: 1337531-36-8

Physical and Chemical Properties
Formula: C24H20F3N5O
Molecular Weight: 451.44
Solubility: DMSO 80 mg/mL
Long-term Storage: at -20℃
Chemical Structure: GSK2606414 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: GSK2606414 is an orally available, potent, and selective PERK inhibitor with IC50 of 0.4 nM, displaying at least 100-fold selectivity over the other EIF2AKs assayed.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.