|Product Name:||GSK1120212 (Trametinib)|
|Long-term Storage:||at -20°C|
|HPLC:||Shows Min 100.00% purity|
|H-NMR:||Consistent with structure|
|Description:||GSK1120212 (JTP-74057) is a highly potent and selective MEK inhibitor with IC50 values to be 0.7 and 0.9 nM for MEK1 and MEK2 respectively and with long circulating half-life.|
|Stability and Solubility Advice:|| Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.