Certificate of Analysis
| Product Name: | GSK-843 |
| Catalog Number: | M13358 |
| CAS Number: | 1601496-05-2 |
Physical and Chemical Properties
| Formula: | C19H15N5S2 |
| Molecular Weight: | 377.49 |
| Solubility: | DMSO ≥ 40 mg/mL |
| Storage: | -20°C, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 98.4% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | GSK-843 is a potent receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 8.6 nM, and inhibits kinase activity with an IC50 of 6.5 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |