Certificate of Analysis

 

Product Name: Gemcabene
Catalog Number: M21472
CAS Number: 183293-82-5

Physical and Chemical Properties
Formula: C16H30O5
Molecular Weight: 302.41
Solubility: DMSO ≥ 60 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Gemcabene Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: Gemcabene (PD-72953) is a first-in-class PPARα agonist, lipid-lowering agent. It lowers density lipoprotein cholesterol (LDL-C), lowers triglycerides and increases high density lipoprotein cholesterol (HDL-C), and lowers the pro-inflammatory acute phase protein, C-reactive protein (CRP), showing anti-inflammatory activity.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.