Certificate of Analysis

 

Product Name: Fostamatinib disodium
Catalog Number: M1847
CAS Number: 1025687-58-4

Physical and Chemical Properties
Formula: C23H24FN6O9PNa2
Molecular Weight: 624.42
Solubility: DMSO 18 mg/mL (ultrasonic and warming)
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Fostamatinib disodium Structure
Analytical Data
QC Standard: >99.0%
H-NMR: Consistent with structure
Product Information
Description: Fostamatinib disodium (R788, R-935788) is a potent, ATP-competitive and selective Syk (Spleen tyrosine kinase) inhibitor with IC50 of 41 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.