Certificate of Analysis

 

Product Name: ETP-46464
Catalog Number: M2187
CAS Number: 1345675-02-6

Physical and Chemical Properties
Formula: C30H22N4O2
Molecular Weight: 470.52
Solubility: DMSO 6 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: ETP-46464 Structure
Analytical Data
QC Standard: 100.00%
H-NMR: Consistent with structure
Product Information
Description: ETP-46464 is a potent inhibitor against mTOR, ATR, DNA-PK, PI 3-Kα and ATM with IC50 of 0.6, 14, 36, 170 and 545 nM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.