Certificate of Analysis

 

Product Name: ERB 041
Catalog Number: M6717
CAS Number: 524684-52-4

Physical and Chemical Properties
Formula: C15H10FNO3
Molecular Weight: 271.24
Solubility: DMSO 27.12 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: ERB 041 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: ERB 041 is a potent and selective estrogen receptor β (ERβ) agonist, with IC50s of 5.4, 3.1, and 3.7 nM for ERβ in humans, rats, and mice, respectively.ERB 041 is more than 200 times more selective for ERβ than for ERα. In addition, ERB 041 inhibits the WNT/β-catenin signaling pathway and induces apoptosis in ovarian cancer cells.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.