Certificate of Analysis

 

Product Name: EPZ020411 hydrochloride
Catalog Number: M11033
CAS Number: 2070015-25-5

Physical and Chemical Properties
Formula: C25H39ClN4O3
Molecular Weight: 479.05516
Solubility: DMSO ≥ 60 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: EPZ020411 hydrochloride  Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: EPZ020411 hydrochloride is a potent and selective PRMT6 inhibitor, IC50 10 nM, which is more than 10 times more selective than acting on PRMT1 and PRMT8.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.