Certificate of Analysis

 

Product Name: Degarelix (GSK1278863)
Catalog Number: M10250
CAS Number: 214766-78-6

Physical and Chemical Properties
Formula: C82H103ClN18O16
Molecular Weight: 1632.26
Solubility: DMSO 10 mg/mL; Water 5 mg/mL (ultrasonic and warming)
Storage: -20°C, dry, sealed
Chemical Structure: Degarelix (GSK1278863) Structure
Analytical Data
QC Standard: >99.5%
H-NMR: Consistent with structure
Product Information
Description: Degarelix (GSK1278863) is a third generation antagonist of luteinizing hormone-releasing hormone (LHRH, also termed gonadotropin-releasing hormone) for the first-line treatment of androgen-dependent advanced prostate cancer.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.