Certificate of Analysis


Catalog Number: M5027
Product Name: CPI-169 racemate
CAS Number: 1450655-76-1

Physical and Chemical Properties
Formula: C27H36N4O5S
Molecular Weight: 528.66
Solubility: DMSO > 80 mg/ml
Long-term Storage: at -20°C
Chemical Structure: CPI-169 racemate Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: CPI-169 racemate is the racemate form of CPI-169, which is a novel and potent EZH2 inhibitor with IC50 <1 nM(inhibition of the catalytic activity of PRC2); decreases cellular levels of H3K27me3 with an EC50 of 70 nM, and triggers cell cycle arrest and apoptosis in a variety of cell lines.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.