Certificate of Analysis
| Product Name: | Cilastatin sodium |
| Catalog Number: | M6603 |
| CAS Number: | 81129-83-1 |
Physical and Chemical Properties
| Formula: | C16H25N2NaO5S |
| Molecular Weight: | 380.43 |
| Solubility: | DMSO 4 mg/mL; Water 8 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98.5% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Cilastatin sodium is a reversible, competitive renal dehydropeptidase I inhibitor with IC50 of 0.1 μM, it inhibits the bacterial metallob-lactamase enzyme CphA with an IC50 of 178 μM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |