Certificate of Analysis

 

Catalog Number: M6178
Product Name: Chidamide
CAS Number: 743420-02-2

Physical and Chemical Properties
Formula: C22H19FN4O2
Molecular Weight: 390.41
Solubility: 78 mg/mL in DMSO
Long-term Storage: at -20°C
Chemical Structure: Chidamide Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Chidamide is a low nanomolar inhibitor of HDAC1, 2, 3, and 10, the HDAC isotypes well documented to be associated with the malignant phenotype with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.