Certificate of Analysis


Catalog Number: M5318
Product Name: CH5183284
CAS Number: 1265229-25-1

Physical and Chemical Properties
Formula: C20H16N6O
Molecular Weight: 356.38
Solubility: 71 mg/mL in DMSO
Long-term Storage: at -20°C
Chemical Structure: CH5183284 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: CH5183284 is a selective and orally available FGFR inhibitor with IC50 of 9.3 nM, 7.6 nM, 22 nM, and 290 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. Phase 1.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.