Certificate of Analysis

 

Product Name: Zoligratinib
Catalog Number: M5318
CAS Number: 1265229-25-1

Physical and Chemical Properties
Formula: C20H16N6O
Molecular Weight: 356.38
Solubility: 71 mg/mL in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Zoligratinib Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: CH5183284 is a selective and orally available FGFR inhibitor with IC50 of 9.3 nM, 7.6 nM, 22 nM, and 290 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. Phase 1.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.