Certificate of Analysis

 

Product Name: CD532 
Catalog Number: M28750
CAS Number: 1639009-81-6

Physical and Chemical Properties
Formula: C26H25F3N8O
Molecular Weight: 522.52
Solubility: DMSO 250 mg/mL (ultrasonic)
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
Chemical Structure: CD532  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: CD532 is a potent Aurora A kinase inhibitor with an IC50 of 45 nM. CD532 has the dual effect of blocking Aurora A kinase activity and driving degradation of MYCN. CD532 also can directly interact with AURKA and induces a global conformational shift. CD532 can be used for the research of cancer.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.