Certificate of Analysis

 

Product Name: CAN508
Catalog Number: M11247
CAS Number: 140651-18-9

Physical and Chemical Properties
Formula: C9H10N6O
Molecular Weight: 218.22
Solubility: DMSO ≥ 200 mg/mL
Storage: 4°C, protect from light, dry, sealed
Chemical Structure: CAN508  Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: CAN508 was an effective AND ATP-competitive inhibitor of CDK9/cyclin T1 with IC50 of 0.35 μM. CAN508 is 38 times more selective for CDK9/cyclin T1 than other CDK/cyclin. CAN508 has antitumor activity.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.