Certificate of Analysis

 

Catalog Number: M2347
Product Name: (+)-Bicuculline
CAS Number: 485-49-4

Physical and Chemical Properties
Formula: C20H17NO6
Molecular Weight: 367.35
Solubility: DMSO 60 mg/mL
Long-term Storage: at -20℃
Chemical Structure: (+)-Bicuculline Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: (+)-Bicuculline is a competitive antagonist of GABAA receptors with IC50 of 2 μM, also blocks Ca(2+)-activated potassium channels.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.