Certificate of Analysis

 

Product Name: Afatinib (BIBW 2992)
Catalog Number: M1677
CAS Number: 850140-72-6

Physical and Chemical Properties
Formula: C24H25ClFN5O3
Molecular Weight: 485.94
Form: Solid
Solubility: DMSO ≥ 80 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Afatinib (BIBW 2992) Structure
Analytical Data
QC Standard: 98.42%
H-NMR: Consistent with structure
Product Information
Description: Afatinib (BIBW 2992) is a novel irreversible dual EGFR and HER2 tyrosine kinase inhibitor.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.