Certificate of Analysis
| Product Name: | Bazedoxifene |
| Catalog Number: | M22417 |
| CAS Number: | 198481-32-2 |
Physical and Chemical Properties
| Formula: | C30H34N2O3 |
| Molecular Weight: | 470.6 |
| Form: | Solid |
| Solubility: | DMSO 95 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98.50% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Bazedoxifene (TSE-424) is an oral, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |