Certificate of Analysis
| Product Name: | AZD-9574 |
| Catalog Number: | M21446 |
| CAS Number: | 2756333-39-6 |
Physical and Chemical Properties
| Formula: | C21H22F2N6O2 |
| Molecular Weight: | 428.44 |
| Solubility: | DMSO ≥ 60 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ＞99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | AZD-9574 is a best-in-class, potent, blood-brain barrier permeable PARP1 inhibitor that exhibits >8000-fold selectivity for PARP1 over PARP2/3/5a/6.AZD-9574 selectively inhibits PARP1 at the SSB site.AZD-9574 is an anticancer AZD-9574 is an anticancer compound that can be used in HRD+ breast cancer and advanced solid malignant tumor studies. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |