Certificate of Analysis

 

Catalog Number: M5099
Product Name: AZD-9291 (Mesylate)
CAS Number: 1421373-66-1

Physical and Chemical Properties
Formula: C29H37N7O5S
Molecular Weight: 595.71
Solubility: 10 mM in DMSO
Long-term Storage: at -20℃
Chemical Structure: AZD-9291 (Mesylate) Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: AZD-9291 is a potent and selective mutated forms EGFR inhibitor(Exon 19 deletion EGFR IC50=12.92 nM, L858R/T790M EGFR IC50= 11.44 nM, wild type EGFR IC50= 493.8 nM).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.