Certificate of Analysis


Catalog Number: M5314
Product Name: AZD-8835
CAS Number: 1620576-64-8

Physical and Chemical Properties
Formula: C22H31N9O3
Molecular Weight: 469.54
Solubility: 93 mg/mL in DMSO
Long-term Storage: at -20°C
Chemical Structure: AZD-8835 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: AZD8835 ia a novel mixed inhibitor of PI3Kα and PI3Kδ with IC50 of 6.2 nM and 5.7 nM, respectively, also with selectivity against PI3Kβ (IC50=431 nM) and PI3Kγ (IC50=90 nM).
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.