Certificate of Analysis
| Product Name: | AZ13705339 hemihydrate |
| Catalog Number: | M31006 |
Physical and Chemical Properties
| Formula: | C33H36FN7O3S.1/2H2O |
| Molecular Weight: | 638.77 |
| Form: | Solid |
| Solubility: | DMSO 100 mg/mL (ultrasonic) |
| Storage: | Powder -20°C |
Analytical Data
| QC Standard: | ≥99.0% |
Product Information
| Description: | AZ13705339 hemihydrate is a highly potent and selective PAK1 inhibitor with IC50s of 0.33 nM and 59 nM for PAK1 and pPAK1, respectively. AZ13705339 hemihydrate has binding affinities to PAK1 and PAK2, with Kds of 0.28 nM and 0.32 nM, respectively. AZ13705339 hemihydrate can be used in the research of cancers. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |