Certificate of Analysis

 

Product Name: Asciminib hydrochloride
Catalog Number: M54849
CAS Number: 2119669-71-3

Physical and Chemical Properties
Formula: C20H19Cl2F2N5O3
Molecular Weight: 486.30
Solubility: DMSO 95 mg/mL
Storage: 4°C, dry, sealed
Chemical Structure: Asciminib hydrochloride Structure
Analytical Data
QC Standard: >98.0%
H-NMR: Consistent with structure
Product Information
Description: Asciminib (ABL001) hydrochloride is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.