Certificate of Analysis

 

Product Name: AS-041164 
Catalog Number: M30394
CAS Number: 6318-41-8

Physical and Chemical Properties
Formula: C11H7NO4S
Molecular Weight: 249.24
Form: Solid
Solubility: DMSO 125 mg/mL (ultrasonic)
Storage: 4°C, protect from light
Chemical Structure: AS-041164  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: AS-041164 is a potent, selective and orally active PI3Kγ isoform inhibitor with an IC50 of 70 nM. AS-041164 shows less activity against PI3Kα, PI3Kβ, and PI3Kδ (IC50s of 240 nM, 1.45 μM, and 1.70 μM, respectively). AS-041164 has anti-inflammatory effects.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.