Product Name: | APX-115 |
Catalog Number: | M9608 |
CAS Number: | 1270084-92-8 |
Formula: | C17H17N3O |
Molecular Weight: | 279.34 |
Form: | Solid |
Solubility: | DMSO ≥ 60 mg/mL |
Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Chemical Structure: |
QC Standard: | >99% |
H-NMR: | Consistent with structure |
Description: | APX-115 is a potent, orally active inhibitor of pan NADPH oxidase (Nox) with Ki of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |