Certificate of Analysis


Catalog Number: M2383
Product Name: AMG-517
CAS Number: 659730-32-2

Physical and Chemical Properties
Formula: C20H13F3N4O2S
Molecular Weight: 430.4
Solubility: DMSO 68 mg/mL
Storage: at -20°C
Chemical Structure: AMG-517 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: AMG 517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.