Certificate of Analysis

 

Product Name: AMG 511
Catalog Number: M3679
CAS Number: 1253573-53-3

Physical and Chemical Properties
Formula: C22H28FN9O3S
Molecular Weight: 517.6
Solubility: DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: AMG 511 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: AMG 511, a potent and selective pan class I PI3K inhibitor exhibiting IC50 values of 8, 11, 2, and 6 nM against the PI3K α, β, δ, and γ isoforms respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.