Certificate of Analysis
| Product Name: | Akt3 degrader 1 |
| Catalog Number: | M29837 |
| CAS Number: | 2836342-69-7 |
Physical and Chemical Properties
| Formula: | C53H72N8O4 |
| Molecular Weight: | 885.19 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Akt3 degrader 1 (compound 12l) is a selective Akt3 degrader that overcomes Osimertinib-induced resistance in H1975OR NSCLC cells. Akt3 degrader 1 also has anti-proliferative activity and significantly inhibits tumour growth in mice. Akt3 degrader 1 can be used in the study of drug-resistant non-small cell lung cancer. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |