Certificate of Analysis

 

Product Name: AGN 194310
Catalog Number: M10777
CAS Number: 229961-45-9

Physical and Chemical Properties
Formula: C28H24O2S
Molecular Weight: 424.55
Solubility: DMSO ≥ 20 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: AGN 194310 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: AGN 194310 (VTP-194310) is a highly affinity, potent, selective pan antagonist of retinoic acid receptors (RARs) against RARα, RARβ, RARγ Kd The values are 3 nM, 2 nM, and 5 nM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.