Certificate of Analysis

 

Catalog Number: M5308
Product Name: Afuresertib
CAS Number: 1047644-62-1

Physical and Chemical Properties
Formula: C18H17Cl2FN4OS
Molecular Weight: 427.32
Solubility: 85 mg/mL in DMSO
Long-term Storage: at -20℃
Chemical Structure: Afuresertib Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Afuresertib (GSK2110183) is a potent, orally bioavailable Akt inhibitor with Ki of 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.