Certificate of Analysis
| Product Name: | Afuresertib |
| Catalog Number: | M5308 |
| CAS Number: | 1047644-62-1 |
Physical and Chemical Properties
| Formula: | C18H17Cl2FN4OS |
| Molecular Weight: | 427.32 |
| Solubility: | DMSO 90 mg/mL |
| Storage: | -20°C, protect from light, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Afuresertib (GSK2110183; LAE002) is a potent, orally bioavailable Akt inhibitor with Ki of 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |