Certificate of Analysis
| Product Name: | AC 187 TFA |
| Catalog Number: | M50214 |
| CAS Number: | 151804-77-2 (free base) |
Physical and Chemical Properties
| Formula: | C129H206F3N37O42 |
| Molecular Weight: | 3004.27 |
| Form: | Solid |
| Solubility: | Water 100 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | AC 187 TFA is a potent, orally active and neuroprotective amylin receptor antagonist with an IC50 of 0.48 nM and a Ki of 0.275 nM. AC 187 TFA is more selective for amylin receptors than calcitonin and CGRP receptors. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |