Certificate of Analysis

 

Product Name: AB-680
Catalog Number: M10772
CAS Number: 2105904-82-1

Physical and Chemical Properties
Formula: C20H24ClFN4O9P2
Molecular Weight: 580.83
Form: Solid
Solubility: DMSO ≥ 150 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: AB-680  Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: AB-680 is a potent, reversible, selective CD73 (extracellular nucleotide enzyme) inhibitor of hCD73 Ki The value is 4.9 pM, which is more than 10,000 times more selective than the associated extracellular nucleotide CD39. Has antitumor activity.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.