Certificate of Analysis

 

Product Name: 9-Aminocamptothecin
Catalog Number: M25388
CAS Number: 91421-43-1

Physical and Chemical Properties
Formula: C20H17N3O4
Molecular Weight: 363.37
Solubility: DMSO 3 mg/mL (Need ultrasonic)
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: 9-Aminocamptothecin Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: 9-Aminocamptothecin (9-amino-CPT) is a topoisomerase I inhibitor with potent anticancer activity. 9-Aminocamptothecin inhibits PC-3, PC-3M, DU145, and LNCaP cells with IC50 values of 34.1, 10, 6.5, and 8.9 nM, respectively after 96 h exposure.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.