Certificate of Analysis
| Product Name: | 18alpha-Glycyrrhetinic acid |
| Catalog Number: | M18197 |
| CAS Number: | 1449-05-4 |
Physical and Chemical Properties
| Formula: | C30H46O4 |
| Molecular Weight: | 470.68 |
| Form: | Solid |
| Solubility: | DMSO 11 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥98.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | 18α-Glycyrrhetinic acid (18α-GA) is a bioactive triterpenoid found in licorice. It is an inhibitor of NF-kB and an activator of proteasome, which serves as pro-longevity and anti-aggregation factor in a multicellular organism. It shows selective inhibition of 11-HSD1 (11-hydroxysteroid dehydrogenase 1). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |