About 16 results found for searched term "TNF-alpha" (0.283 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6222 | Adalimumab | TNF Receptor |
| LU200134, D2E7, Anti-Human TNF-alpha | ||
| Adalimumab is the first fully human, recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha, MW: 144.19 KD. | ||
| M11495 | Recombinant Human TNF-α (E. coli) | Recombinant Proteins |
| TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Cachectin | ||
| Recombinant human TNF-α protein (E. coli) is a homotrimer with a subunit molecular mass of 17.3 kDa. TNF-a plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases; and in viral, bacterial, fungal, and parasitic infections. ED50 < 30.0 pg/ml, measured in a cytotoxicity assay using L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D, corresponding to a specific activity of > 3.3 × 107 units/mg. | ||
| M21466 | Recombinant Rat TNF-α (P. pastoris) | Recombinant Proteins |
| TNF-alpha; Tumor necrosis factor ligand superfamily member 2 | ||
| Recombinant rat tumor necrosis factor produced in Pichia pastoris. TNF-alpha plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune disease. ED50 < 50.0 pg/ml | ||
| M51703 | Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) | Fluorescent Dye |
| Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) is a peptide. | ||
| M4378 | Forsythoside B | TNF Receptor |
| Forsythoside B inhibits TNF-alpha, IL-6, IκB and modulate NF-κB. | ||
| M10468 | N-Formyl-Met-Leu-Phe | FPR |
| fMLP | ||
| N-Formyl-Met-Leu-Phe (fMLP) is a chemotactic peptide and a specific ligand of N-formyl peptide receptor (FPR), which can inhibit TNF-alpha secretion. | ||
| M11179 | CPI-1189 | TNF Receptor |
| REN 1654, REN 1189 | ||
| CPI-1189 (REN 1654, REN 1189) is an inhibitor of tumor necrosis factor (TNF) alpha. CPI-1189 inhibits the phosphorylation activation of protein kinase activated by p38 mitogens in cells and plays a neuroprotective role. | ||
| M14162 | Cot inhibitor-1 | p38 MAPK |
| Cot inhibitor-1 (compound 28) is a selective tumor progression loci-2 (Tpl2) kinase inhibitor with an IC50 of 28 nM. Cot inhibitor-1 shows an inhibition of TNF-alpha production in human whole blood with an IC50 of 5.7 nM. | ||
| M24891 | Opinercept | TNF Receptor |
| Opinercept is a tumor necrosis factor-alpha (TNF-alpha) inhibitor. Opinercept can be used for the research of rheumatoid arthritis (RA). | ||
| M25324 | Licaminlimab | TNF Receptor |
| OCS-02 | ||
| Licaminlimab (OCS-02) is a single-chain anti-TNF alpha antibody fragment. TNF alpha is an inflammatory cytokine produced by macrophages and monocytes during inflammation. | ||
| M28589 | SP-100030 | NF-κB |
| SP-100030 is a potent NF-κB and activator protein-1 (AP-1) double inhibitor (IC50s=50 and 50 nM, respectively). SP-100030 inhibits IL-2, IL-8, and TNF-alpha production in Jurkat and other T cell lines. SP-100030 decreases murine collagen-induced arthritis (CIA). | ||
| M29166 | TNF-α-IN-2 | TNF Receptor |
| TNF-α-IN-2 is a potent and orally active inhibitor of tumor necrosis factor alpha (TNFα), with an IC50 of 25 nM in the HTRF assay. TNF-α-IN-2 distorts the TNFα trimer upon binding, leading to aberrant signaling when the trimer binds to TNFR1. TNF-α-IN-2 can be used for the research of rheumatoid arthritis. | ||
| M29272 | GW-3333 | TNF Receptor |
| GW-3333 is a potent and orally active TNF-alpha-converting enzyme (TACE) and matrix metalloproteinases (MMP) inhibitor. GW-3333 inhibits tumor necrosis factor-alpha (TNF-alpha) production and arthritis. | ||
| M31421 | Isomyosmine | TNF Receptor |
| Isomyosmine is an orally active inhibitor of TNF-alpha that can be used in studies related to sarcopenia as well as chronic inflammation. | ||
| M40776 | Oxazolone | Animal Modeling |
| OXA; OXZ | ||
| Oxazolone is a semi-antagonist that induces acute or chronic colorectal inflammation and is used to construct models of colitis, as well as models of airway allergic disease.Oxazolone-induced inflammation can be attenuated by neutralizing anti-IL-4 or anti-TNF-alpha antibodies, or by the decoy IL-13R2α-Fc protein. | ||
| M41379 | BMS-561392 | TNF Receptor |
| BMS-561392 is a TNF alpha-converting enzyme (TACE) inhibitor. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
