About 3 results found for searched term "Pifithrin-α" (0.145 seconds)
Cat.No. | Name | Target |
---|---|---|
M2036 | Pifithrin-α | p53 |
Pifithrin hydrobromide; PFTα hydrobromide | ||
Pifithrin-α is an inactivator of p53 that blocks p53-dependent transcriptional activation and apoptosis. | ||
M8014 | Cyclic Pifithrin-α hydrobromide | p53 |
Cyclic Pifithrin-α hydrobromide; Cyclic PFT-α hydrobromide; PFT-β hydrobromide | ||
Cyclic Pifithrin-α hydrobromide is a stabilized pifithrin-α analog as well as a specific p53 inhibitor with low cytotoxicity. | ||
M30033 | p-nitro-Pifithrin-α | p53 |
p-nitro-Pifithrin-α, a cell-permeable analog of pifithrin-α, is a potent p53 inhibitor. p-nitro-Pifithrin-α suppresses p53-mediated TGF-β1 expression in HK-2 cells. p-nitro-Pifithrin-α inhibits the activation of caspase-3 by Zika virus (ZIKV) strains. p-nitro-Pifithrin-α attenuates steatosis and liver injury in mice fed a high-fat diet . non-alcoholic fatty liver disease. |
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