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 About 1 result found for searched term "Larotrectinib (LOXO-101)" (0.082 seconds)

Cat.No.  Name Target
M6151 Larotrectinib (LOXO-101) Trk
ARRY-470, larotrectinib
Larotrectinib (LOXO-101) is a potent, ATP competitive TRK inhibitor with IC50s in low nanomolar range for inhibition of all TRK family members in binding and cellular assays, with 100x selectivity over other kinases, with 2 to 20 nM cellular potency against the TRKA, TRKB, and TRKC kinases.

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