About 2 results found for searched term "Grisnilimab" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M25090 | Grisnilimab setaritox | Others |
| WT1-RTA | ||
| Grisnilimab setaritox (WT1-RTA), is an antihuman T cell antibody (anti-CD7) conjugating with ricin A chain (RTA). RTA is a 30-kDa peptide capable of rapidly in activating ribosomal 60S subunits. Grisnilimab setaritox is cytotoxic to CEM (T-lymphoblastic leukemia) cells in vitro with an ID50 of 53 pM. Grisnilimab setaritox also improves leukemic meningitis model in rhesus monkeys. | ||
| M25095 | Grisnilimab | Others |
| WT1 | ||
| Grisnilimab (WT1), a IgG2a monoclonal antibody anti-CD7, is a tumor suppressor involved in the etiology of Wilms' tumor. Grisnilimab regulates the transcription of multiple target genes and may participate in the post-transcriptional processing of RNA. | ||
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