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 About 28 results found for searched term "Glucagon Receptor" (0.036 seconds)

Cat.No.  Name Information
M1601 Dulaglutide (Activated main chain) Dulaglutide (Activated main chain) is a glucagon-like peptide-1 receptor agonist (GLP-1 agonist) consisting of GLP-1(7-37) covalently linked to an Fc fragment of human IgG4.
M4344 Shanzhiside-methylester Shanzhiside Methyl ester was isolated from Lactobacillus rotaformis. Shanzhiside Methyl ester, a small molecule glucagon-like peptide 1 (GLP-1 receptor) agonist, has the ability to induce anti-abnormal pain tolerance.
M6878 L-168,049 L-168,049 is a potent, orally active human glucagon receptor antagonist.
M9487 Tirzepatide hydrochloride Tirzepatide Hydrochloride is a first-in-class glucose-dependent insulin-stimulating peptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist for the study of diabetes mellitus.
M8101 PF-06412154 hydrochloride PF-06412154 hydrochloride is a glucagon receptor antagonist.
M8113 PF-06291874 PF-06291874 is an orally active, potent and selective glucagon receptor antagonist.
M8394 BETP BETP is an agonist of glucagon-like peptide-1 (GLP-1) receptor, with EC50s of 0.66 and 0.755 μM for human and rat GLP-1 receptor, respectively.
M8940 GRA Ex-25 GRA Ex-25 is an inhibitor of glucagon receptor, with IC50 values of 56 and 55 nM for rat and human glucagon receptors, respectively.
M9190 Lixisenatide Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist, which is a hormone that helps normalize blood sugar levels.
M9311 Liraglutide Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist.
M9749 Cotadutide acetate Cotadutide acetate is a potent peptide dual agonist of glucagon-like peptide-1 (GLP-1) and glucagon receptor, with EC50 values of 6.9 pM and 10.2 pM, respectively.
M10034 Exendin-4 Exenatide (AC2993) is a first-in-class glucagon-like peptide 1 (GLP-1) receptor agonist consisting of 39 amino acids.
M10144 NNC0640 NNC0640 is a potent, negative allosteric modulator (NAM) of human G-protein-coupled glucagon receptor (GCGR) with IC50 of 69.2 nM.
M10311 Danuglipron (PF-06882961) Danuglipron (PF-06882961) is a potent, orally bioavailable agonist of the glucagon-like peptide-1 receptor (GLP-1R) agonist.
M10914 dasiglucagon Dasiglucagon(Zegalogue) is a Glucagon Receptor Agonist. The physiologic effect of dasiglucagon is by means of Increased Glycogenolysis.
M21288 LY3502970 LY3502970 (GLP-1 receptor agonist 1) is a glucagon-like peptide (GLP-1) receptor agonist.
M11428 LSN3318839 LSN3318839 is an orally active allosteric modulator of glucagon-like peptide-1 receptor (GLP-1R).
M13966 Adomeglivant Adomeglivant (LY2409021) is a potent, selective glucagon receptor (GluR) allosteric antagonist. Adomeglivant is widely used in the research for type 2 diabetes mellitus.
M13970 Lixisenatide acetate Lixisenatide acetate is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM).
M13971 MK 0893 MK 0893 is a potent and selective glucagon receptor antagonist with an IC50 of 6.6 nM.
M13972 Semaglutide TFA Semaglutide TFA, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide TFA has the potential for type 2 diabetes treatment.
M21371 Tirzepatide Tirzepatide (LY3298176) is a glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor dual agonist with potential use in type 2 diabetes research.
M21377 PF-06372222 PF-06372222 is a small-molecule negative allosteric modulator of the glucagon receptor (GCGR). PF-06372222 is also an antagonist for glucagon-like peptide-1 receptor GLP-1R, which inhibits glucagon secretion and glucose-dependent insulin secretion.
M21658 Taspoglutide Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist developed for treatment of type 2 diabetes, with an EC50 value of 0.06 nM.
M24584 Volagidemab Volagidemab is an antagonistic glucagon receptor (GCGR) monoclonal antibody (mAb). Volagidemab can be used in the research of type 1 diabetes (T1D).
M24689 Crotedumab Crotedumab (REGN1193) is a fully human IgG4 monoclonal antibody that binds and inhibits glucagon receptor (GCGR), with a KD of 0.1 nM. Crotedumab can be used for the research of diabetes.
M25390 Dapiglutide Dapiglutide (ZP7570) is a long-acting glucagon-like peptide-1 receptor 1R (GLP-1R)/Glucagon-like peptide-2 receptor (GLP-2R) dual agonist.
M25470 Mazdutide Mazdutide (IBI362, LY3305677) is a novel glucagon-like peptide-1 (GLP-1) and glucagon receptor dual agonist.

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