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About 30 results found for searched term "Aurora Kinase" (0.032 seconds)
| Cat.No. | Name | Information |
|---|---|---|
| M1655 | AT9283 | AT9283 is a potent inhibitor of several protein kinases, including Aurora A, Aurora B, Janus kinase 2 (JAK2), JAK3, and ABL. |
| M1691 | CCT-129202 | CCT129202 is an Aurora kinase inhibitor with IC50 of 0.042 ± 0.022, 0.198 ± 0.05, and 0.227 ± 0.064 μmol/L for Aurora A, Aurora B, and Aurora C, respectively. |
| M1706 | ENMD-2076 | ENMD-2076 is an orally-active, Aurora A/angiogenic kinase inhibitor. |
| M1752 | MLN8237 (Alisertib) | MLN8237 (Alisertib) is a second-generation, orally bioavailable, highly selective Aurora kinase A inhibitor with IC50 of 61 nM. |
| M1769 | PHA-739358 (Danusertib) | PHA-739358 (Danusertib) is a small molecule with low nanomolar activity against all aurora kinases (AKs) with IC50 value of 13 nM for aurora-A and 79 nM for aurora-B respectively. |
| M1800 | JNJ-7706621 | JNJ-7706621 is a dual cell cycle inhibitor with activity against cyclin-dependent kinases (CDK1, 2, 3, 6) with an IC50 of 3-175 nM and Aurora kinases (A and B) with an IC50 of 11-15 nM respectively. |
| M1815 | KW-2449 | KW-2449 is a novel multitargeted kinase inhibitor of FLT3, ABL and Aurora kinase with IC50 values of 6.6 nM, 14 nM and 48 nM. |
| M1877 | ZM447439 | ZM447439 is the first Aurora family kinase inhibitor with IC50 of 50 nM for Aurora B kinase. |
| M1881 | Tozasertib | Tozasertib (VX-680, MK-0457) is a potent and selective pan-Aurora kinase inhibitor active against all Bcr/Abl proteins. |
| M2103 | CCT137690 | CCT137690 is a potent inhibitor of Aurora kinases with IC50 values of 15, 19 and 25 nM at Aurora A, Aurora C and Aurora B respectively. |
| M2127 | Hesperadin | Hesperadin is an ATP-competitive inhibitor of Aurora B kinase with IC50 of 250 nM. |
| M2169 | AMG 900 | AMG 900 is a potent and selective, orally available small molecule aurora kinase inhibitor. |
| M2188 | Reversine | Reversine is a novel small molecule ATP-competitive Aurora kinase inhibitor with IC50 of 98.5 nM for Aurora B. |
| M3931 | Aurora Kinase Inhibitor III | Aurora Kinase Inhibitor III is a strong and selective Aurora A kinase inhibitor with an IC50 of 42 nM. |
| M5236 | BI-847325 | BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively. |
| M7363 | TC-A 2317 hydrochloride | TC-A 2317 hydrochloride is a potent, selective Aurora kinase A inhibitor. |
| M7393 | TC-S 7010 | TC-S 7010 is a potent and selective Aurora kinase A inhibitor. |
| M7986 | OM137 | OM137 is an inhibitor of aurora kinases; inhibitor of spindle checkpoint. |
| M8042 | CP-335963 | CP-335963 is an aurora 2 kinase inhibitor, PDGF inhibitor, and anti-proliferative. |
| M9895 | LY3295668 | LY3295668 (AK-01) is a potent, orally active and highly specific Aurora-A kinase inhibitor, with Ki values of 0.8 nM and 1038 nM for AurA and AurB, respectively. |
| M10945 | Chiauranib | Chiauranib (CS2164) is a multi-target inhibitor with oral activity against tumor angiogenesis. Chiauranib effectively inhibits angiogenesis-associated kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRα and c-Kit), mitosis-associated kinase Aurora B, and chronic inflammation-associated kinase CSF-1R,IC50 The value is 1-9 nM. Chiauranib has a strong anti-cancer effect. |
| M13591 | Cenisertib | Cenisertib (AS-703569) is an ATP-competitive multi-kinase inhibitor that blocks the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5 and FLT3. |
| M20235 | WAY-632963 | WAY-632963 is a Aurora kinase A inhibitor. |
| M20238 | WAY-634704 | WAY-634704 is a Aurora kinase A inhibitor. |
| M20244 | WAY-635764 | WAY-635764 is a Aurora kinase A inhibitor. |
| M20245 | WAY-635767 | WAY-635767 is a Aurora kinase A inhibitor |
| M20246 | WAY-636900 | WAY-636900 is a Aurora kinase A inhibitor. |
| M20247 | WAY-636982 | WAY-636982 is a Aurora kinase A inhibitor. |
| M20251 | WAY-638641 | WAY-638641 is a Aurora kinase A inhibitor. |
| M20284 | WAY-661516 | WAY-661516 is a Aurora kinase A inhibitor. |
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