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 About 30 results found for searched term "Aurora Kinase" (0.032 seconds)

Cat.No.  Name Information
M1655 AT9283 AT9283 is a potent inhibitor of several protein kinases, including Aurora A, Aurora B, Janus kinase 2 (JAK2), JAK3, and ABL.
M1691 CCT-129202 CCT129202 is an Aurora kinase inhibitor with IC50 of 0.042 ± 0.022, 0.198 ± 0.05, and 0.227 ± 0.064 μmol/L for Aurora A, Aurora B, and Aurora C, respectively.
M1706 ENMD-2076 ENMD-2076 is an orally-active, Aurora A/angiogenic kinase inhibitor.
M1752 MLN8237 (Alisertib) MLN8237 (Alisertib) is a second-generation, orally bioavailable, highly selective Aurora kinase A inhibitor with IC50 of 61 nM.
M1769 PHA-739358 (Danusertib) PHA-739358 (Danusertib) is a small molecule with low nanomolar activity against all aurora kinases (AKs) with IC50 value of 13 nM for aurora-A and 79 nM for aurora-B respectively.
M1800 JNJ-7706621 JNJ-7706621 is a dual cell cycle inhibitor with activity against cyclin-dependent kinases (CDK1, 2, 3, 6) with an IC50 of 3-175 nM and Aurora kinases (A and B) with an IC50 of 11-15 nM respectively.
M1815 KW-2449 KW-2449 is a novel multitargeted kinase inhibitor of FLT3, ABL and Aurora kinase with IC50 values of 6.6 nM, 14 nM and 48 nM.
M1877 ZM447439 ZM447439 is the first Aurora family kinase inhibitor with IC50 of 50 nM for Aurora B kinase.
M1881 Tozasertib Tozasertib (VX-680, MK-0457) is a potent and selective pan-Aurora kinase inhibitor active against all Bcr/Abl proteins.
M2103 CCT137690 CCT137690 is a potent inhibitor of Aurora kinases with IC50 values of 15, 19 and 25 nM at Aurora A, Aurora C and Aurora B respectively.
M2127 Hesperadin Hesperadin is an ATP-competitive inhibitor of Aurora B kinase with IC50 of 250 nM.
M2169 AMG 900 AMG 900 is a potent and selective, orally available small molecule aurora kinase inhibitor.
M2188 Reversine Reversine is a novel small molecule ATP-competitive Aurora kinase inhibitor with IC50 of 98.5 nM for Aurora B.
M3931 Aurora Kinase Inhibitor III Aurora Kinase Inhibitor III is a strong and selective Aurora A kinase inhibitor with an IC50 of 42 nM.
M5236 BI-847325 BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively.
M7363 TC-A 2317 hydrochloride TC-A 2317 hydrochloride is a potent, selective Aurora kinase A inhibitor.
M7393 TC-S 7010 TC-S 7010 is a potent and selective Aurora kinase A inhibitor.
M7986 OM137 OM137 is an inhibitor of aurora kinases; inhibitor of spindle checkpoint.
M8042 CP-335963 CP-335963 is an aurora 2 kinase inhibitor, PDGF inhibitor, and anti-proliferative.
M9895 LY3295668 LY3295668 (AK-01) is a potent, orally active and highly specific Aurora-A kinase inhibitor, with Ki values of 0.8 nM and 1038 nM for AurA and AurB, respectively.
M10945 Chiauranib Chiauranib (CS2164) is a multi-target inhibitor with oral activity against tumor angiogenesis. Chiauranib effectively inhibits angiogenesis-associated kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRα and c-Kit), mitosis-associated kinase Aurora B, and chronic inflammation-associated kinase CSF-1R,IC50 The value is 1-9 nM. Chiauranib has a strong anti-cancer effect.
M13591 Cenisertib Cenisertib (AS-703569) is an ATP-competitive multi-kinase inhibitor that blocks the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5 and FLT3.
M20235 WAY-632963 WAY-632963 is a Aurora kinase A inhibitor.
M20238 WAY-634704 WAY-634704 is a Aurora kinase A inhibitor.
M20244 WAY-635764 WAY-635764 is a Aurora kinase A inhibitor.
M20245 WAY-635767 WAY-635767 is a Aurora kinase A inhibitor
M20246 WAY-636900 WAY-636900 is a Aurora kinase A inhibitor.
M20247 WAY-636982 WAY-636982 is a Aurora kinase A inhibitor.
M20251 WAY-638641 WAY-638641 is a Aurora kinase A inhibitor.
M20284 WAY-661516 WAY-661516 is a Aurora kinase A inhibitor.


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