About 10 results found for searched term "Acetyl-CoA Carboxylase" (0.11 seconds)
Cat.No. | Name | Target |
---|---|---|
M3149 | CP-640186 | Acetyl-CoA Carboxylase |
CP-640186 is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. | ||
M5536 | CP-640186 HCl | Acetyl-CoA Carboxylase |
CP-640186 Hcl is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively; with improved metabolic stability vs CP-610431. | ||
M6137 | PF-05175157 | Acetyl-CoA Carboxylase |
PF05175157 | ||
PF-05175157 is a potent Acetyl-CoA carboxylase (ACC1) inhibitor with IC50s of 23.5±1.1 nM (rat) and 27.0±2.7 nM (human). | ||
M8184 | S-2E | Acetyl-CoA Carboxylase |
S2E | ||
S-2E is an orally active and noncompetitive HMG-CoA reductase and acetyl-CoA carboxylase inhibitor. S-2E has an anti-hyperlipidemic action. | ||
M10670 | Acetyl Coenzyme A trisodium | Enzymes & Coenzymes |
Acetyl coenzyme A sodium salt; Acetyl-CoA trisodium | ||
Acetyl Coenzyme A trisodium (Acetyl-CoA trisodium) is a central metabolic intermediate. Acetyl Coenzyme A trisodium is the actual molecule through which glycolytic pyruvate enters the tricarboxylic acid (TCA) cycle, is a key precursor of lipid synthesis, and is the sole donor of the acetyl groups for acetylation. Acetyl Coenzyme A trisodium acts as a potent allosteric activator of pyruvate carboxylase (PC). | ||
M14290 | MK-4074 | Acetyl-CoA Carboxylase |
MK-4074 is a liver-specific inhibitor of acetyl-CoA carboxylase ACC1 and ACC2 with IC50 values of approximately 3 nM. | ||
M21286 | PF-05221304 | Acetyl-CoA Carboxylase |
Clesacostat | ||
PF-05221304 is an orally bioavailable, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), an enzyme that catalyzes the first step of adipogenesis ab initio (DNL). | ||
M21697 | CMS-121 | Acetyl-CoA Carboxylase |
CMS121 | ||
CMS-121 is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage with EC50 values of 7 nM and 200 nM, respectively. | ||
M30850 | A-908292 | Acetyl-CoA Carboxylase |
A-908292 is a potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor, with an IC50 of 38 nM. A-908292 can be used for the research of fatty acid metabolism. | ||
M31105 | BAY-3827 | AMPK |
BAY3827 | ||
BAY-3827 is a potent AMPK inhibitor which inhibits AMPK kinase activity with IC50 values of 1.4 nM at low (10 µM ATP concentration) and 15 nM at high (2 mM ATP concentration). BAY-3827 prevents phosphorylation of acetyl-CoA carboxylase 1 (ACC1). |
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