About 7 results found for searched term "94-62-2" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5881 | Piperine | P-glycoprotein |
| Bioperine; 1-Piperoylpiperidine | ||
| Piperine, a natural alkaloid isolated from Piper nigrum L, inhibits P-glycoprotein and CYP3A4 activities with an IC50 value of 61.94±0.054 μg/mL in HeLa cell. | ||
| M8790 | MDL-860 | Others |
| MDL-860 is a 5-nitro-2-phenoxybenzonit |
||
| M40222 | Dihydropyrocurzerenone | Others |
| Dihydropyrocurzerenone is a furanosesquiterpene isolated from the resin of Commiphora sphaerocarpa. | ||
| M5325 | GSK 650394 | SGK |
| GSK650394 is a serum- and glucocorticoid-regulated kinase-1 inhibitor with IC50 of 62 nM and 103 nM for SGK1 and SGK2, respectively. | ||
| M9957 | Finerenone | Mineralocorticoid Receptor |
| BAY94-8862 | ||
| Finerenone (BAY 94-8862) is a third generation selective, oral active, non-steroidal halocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone showed good selectivity (>500-fold) compared to glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (AR). Finerenone has potential applications in the study of heart and kidney diseases, such as type 2 diabetes and chronic kidney disease. | ||
| M27934 | AS1949490 | Phosphatase |
| AS1949490 is a potent, orally active, selective SHIP2 phosphatase inhibitor with IC50 values of 0.34, 0.62, 13, >50, >50, and >50 µM for Mouse SHIP2, Human SHIP2, Human SHIP1, Human PTEN, Human synaptojanin, and Human myotubularin, respectively. AS1949490 increases the phosphorylation of Akt, glucose consumption and glucose uptake. AS1949490 activates intracellular insulin signalling pathways. AS1949490 can be used for research of diabetes. | ||
| M42706 | WLB-89462 | Sigma Receptor |
| WLB-89462 is a selective σ2 receptor ligand (Ki: 13 nM). | ||
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