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Sodium lauryl sulfate

Cat. No. M11401
Sodium lauryl sulfate Structure
Size Price Availability Quantity
100g USD 60  USD60 In stock
500g USD 120  USD120 In stock
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Quality Control
Biological Activity

Sodium dodecyl sulfate (SDS) is a kind of anionic surfactant, which is the first reported proteasome agonist, and has the characteristics of low concentration promotion and high concentration inhibition.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 288.38
Formula C12H25NaO4S
CAS Number 151-21-3
Purity
Solubility N/A
Storage 2-8°C
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