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Sodium lauryl sulfate

Cat. No. M11401
Sodium lauryl sulfate Structure
Synonym:

SDS

Size Price Availability Quantity
25g USD 25  USD25 In stock
100g USD 60  USD60 In stock
500g USD 120  USD120 In stock
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Quality Control & Documentation
Biological Activity

Sodium dodecyl sulfate (SDS) is a kind of anionic surfactant, which is the first reported proteasome agonist, and has the characteristics of low concentration promotion and high concentration inhibition.

Chemical Information
Molecular Weight 288.38
Formula C12H25NaO4S
CAS Number 151-21-3
Solubility (25°C) N/A
Storage 2-8°C
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Shaira R Kasi, et al. Am J Dent. Side effects of sodium lauryl sulfate applied in toothpastes: A scoping review

[2] T Agner, et al. Br J Dermatol. Sodium lauryl sulfate: a never ending story?

[3] T J Paul, et al. Br Dent J. Sodium lauryl sulphate

[4] J A F Oosterhaven. Br J Dermatol. Anatomical location differences in sodium lauryl sulfate-induced irritation

[5] Babatunde Y Alli, et al. J Oral Pathol Med. Effect of sodium lauryl sulfate on recurrent aphthous stomatitis: A systematic review

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Keywords: Sodium lauryl sulfate, SDS supplier, Western Blot, inhibitors, activators


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