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Loteprednol etabonate

Cat. No. M3544

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Loteprednol etabonate Structure
Size Price Availability Quantity
5mg USD 30  USD30 In stock
10mg USD 40  USD40 In stock
50mg USD 150  USD150 In stock
100mg USD 250  USD250 In stock
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Quality Control & Documentation
Biological Activity

Loteprednol etabonate is an anti-inflammatory corticosteroid used in ophthalmology. It is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis and selected infective conjunctivitides. As a nasal spray, it is used for the treatment and management of seasonal allergic rhinitis.

Chemical Information
Molecular Weight 466.95
Formula C24H31ClO7
CAS Number 82034-46-6
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Francis S Mah, et al. Review of Loteprednol Etabonate 0.5%/Tobramycin 0.3% in the Treatment of Blepharokeratoconjunctivitis

[2] Kenneth Beckman, et al. Loteprednol Etabonate for the Treatment of Dry Eye Disease

[3] Connie Kang, et al. Loteprednol Etabonate (Submicron) Ophthalmic Gel 0.38%: A Review in Post-Operative Inflammation and Pain Following Ocular Surgery

[4] Katherine A Lyseng-Williamson. Loteprednol etabonate ophthalmic gel 0.5%: a review of its use in post-operative inflammation and pain following ocular surgery

[5] Michael Amon, et al. Loteprednol etabonate ophthalmic suspension 0.5 %: efficacy and safety for postoperative anti-inflammatory use

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