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ERDRP-0519 

Cat. No. M28277

All AbMole products are for research use only, cannot be used for human consumption.

ERDRP-0519  Structure

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Quality Control & Documentation
Biological Activity

ERDRP-0519, an orally bioavailable small-molecule Measles virus (MeV) polymerase inhibitor, prevents measles disease in squirrel monkeys (Saimiri sciureus). ERDRP-0519 inhibits morbilliviruses with nanomolar potency..

Chemical Information
Molecular Weight 529.58
Formula C23H30F3N5O4S
CAS Number 1374006-96-8
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Michele Camero, et al. BMC Vet Res. ERDRP-0519 inhibits feline coronavirus in vitro

[2] Kevin Wittwer, et al. Nat Commun. Small-molecule polymerase inhibitor protects non-human primates from measles and reduces shedding

[3] Robert M Cox, et al. PLoS Pathog. Therapeutic targeting of measles virus polymerase with ERDRP-0519 suppresses all RNA synthesis activity

[4] Richard K Plemper. Curr Opin Virol. Measles Resurgence and Drug Development

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  Catalog
Abmole Inhibitor Catalog




Keywords: ERDRP-0519  supplier, inhibitors, activators

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