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Carboxymethyl cellulose sodium

Cat. No. M9317
Carboxymethyl cellulose sodium Structure
Synonym:

CMC-Na

Size Price Availability Quantity
10g USD 45  USD50 In stock
50g USD 72  USD80 In stock
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Quality Control
  • Current batch:
  • Purity ≥500 mpa.s
  • COA
  • MSDS
Biological Activity

Carboxymethyl cellulose sodium is frequently used as viscous agent, paste and barrier agent.

Product Citations
Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 242.16
Formula C8H16NaO8
CAS Number 9004-32-4
Purity ≥500 mpa.s
Solubility Water ≥ 20 mg/mL
Storage -20°C, dry, sealed
References

Dexamethasone and sodium carboxymethyl cellulose prevent postoperative intraperitoneal adhesions in rats.
Du XH, et al. Braz J Med Biol Res. 2015 Apr;48(4):344-8. PMID: 25714889.

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