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3F8

Cat. No. M6337

All AbMole products are for research use only, cannot be used for human consumption.

3F8 Structure
Size Price Availability
10mg USD 475  USD475 Custom Synthesis
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Quality Control & Documentation
Biological Activity

3F8 is a potent and selective GSK-3β inhibitor (IC50 values are 34 and 304 nM in the presence of 10 and 100 μM ATP respectively).

Chemical Information
Molecular Weight 286.28
Formula C15H14N2O4
CAS Number 159109-11-2
Solubility (25°C) DMSO 7.16 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] No authors listed. Naxitamab

[2] Brian H Kushner, et al. Humanized 3F8 Anti-GD2 Monoclonal Antibody Dosing With Granulocyte-Macrophage Colony-Stimulating Factor in Patients With Resistant Neuroblastoma: A Phase 1 Clinical Trial

[3] Kim Kramer, et al. A phase II study of radioimmunotherapy with intraventricular 131 I-3F8 for medulloblastoma

[4] Brian H Kushner, et al. Posterior reversible encephalopathy syndrome in neuroblastoma patients receiving anti-GD2 3F8 monoclonal antibody

[5] J P Heiner, et al. Localization of GD2-specific monoclonal antibody 3F8 in human osteosarcoma

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  Catalog
Abmole Inhibitor Catalog




Keywords: 3F8 supplier, GSK-3, inhibitors, activators

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