About 13 results found for searched term "Prostaglandin E2" (0.031 seconds)
|M2458||Bismuth Subsalicylate||Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2.|
|M2471||Bromfenac Sodium||Bromfenac is a nonsteroidal anti-inflammatory compound (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.|
|M3809||Isofraxidin||Isofraxidin is an anti-bacterial, anti-oxidant, and anti-inflammatory agent, it acts by reducing the levels of tumor necrosis factor-a (TNF-a), interleukin-6 (IL-6), and prostaglandin E2 (PGE2), inhibiting cyclooxygenase-2 (COX-2) protein expression.|
|M4930||SW033291||SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.|
|M5929||Prostaglandin E2||Prostaglandin E2 is a vasodilator isolated from prostate gland secretion, working by binding and activating the prostaglandin E2 receptor.|
|M8120||PF-04217329||PF-04217329 is a selective and potent prostaglandin EP2 receptor agonist.|
|M8780||ONO-AE3-208||ONO-AE3-208 is an orally active prostaglandin E2 receptor 4 (EP4)-selective antagonist (Ki in nM = 1.|
|M8900||TG6-10-1||TG6-10-1 is a potent and selective antagonist for the prostaglandin E2 receptor subtype EP2.|
|M9232||PF-04418948||PF-04418948 is a novel, potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM.|
|M9277||TG4-155||TG4-155 is a brain penetrant prostaglandin EP2 specific antagonist, with a Ki of 9.9 nM.|
|M10632||AM211||AM-211 is a novel and potent antagonist of the prostaglandin D2 receptor type 2, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively.|
|M10634||NE 52-QQ57||NE 52-QQ57 is an orally available GPR4 antagonist with an IC50 of 70 nM. NE 52-QQ57 significantly inhibited the AGE-induced increased expression of several key inflammatory cytokines and signaling molecules, including tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-6, inducible nitric oxide synthase (iNOS), nitric oxide (NO), cyclooxygenase 2 (COX2), and prostaglandin E2 (PGE2).|
|M10653||Dehydroevodiamine||Dehydroevodiamine has an antiarrhythmic effect in guinea-pig ventricular myocytes. Dehydroevodiamine inhibits LPS-induced iNOS, COX-2, prostaglandin E2 (PGE2) and nuclear factor-kappa B (NF-κB) expression in murine macrophage cells.|
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