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 About 12 results found for searched term "AZ32" (0.053 seconds)

Cat.No.  Name Target
M1696 Cediranib VEGFR/PDGFR
AZD2171; NSC-732208
Cediranib (AZD2171) inhibited VEGFR2 and KDR phosphorylation with IC50s of 0.4 and 0.5 nM, respectively.
M5227 AZD3293 BACE
LY3314814
AZD3293, also known as LY3314814 is an oral beta-secretase 1 cleaving enzyme (BACE) inhibitor.
M5313 AZD2932 VEGFR/PDGFR
AZD2932 is a potent and mutil-targeted protein tyrosine kinase inhibitor with IC50 of 8 nM, 4 nM, 7 nM, and 9 nM for VEGFR-2, PDGFRβ, Flt-3, and c-Kit, respectively.
M5427 Atazanavir HIV Protease
Latazanavir, Zrivada, Reyataz, BMS-232632
Atazanavir is an azapeptide and HIV-protease inhibitor that is used in the treatment of HIV infections and AIDS in combination with other anti-HIV agents.
M6180 AZD3264 IκB/IKK
AZD3264 is a novel IKK2 inhibitor.
M9411 AZD-7325 GABA Receptor
AZD7325
AZD-7325 is a GABA-Aα2,3 -selective receptor modulator.
M10158 AZ32 ATM/ATR
AZ-32
AZ32 is an orally bioavailable and blood-brain barrier-(BBB)penetrating inhibitor of ATM with IC50 of <6.2 nM and 0.31 μM for ATM enzyme in cell.
M10514 Verdiperstat (AZD3241) Others
AZD3241; BHV-3241; CAS#890655-80-8
Verdiperstat (AZD-3241) is a selective and irreversible inhibitor of myeloperoxidase (MPO) with an IC50 of 630 nM.
M20646 AZD3229 c-Kit
AZD3229 is a potent, pan-KIT mutant inhibitor with potent single digit nM growth inhibition against a diverse panel of mutant KIT driven Ba/F3 cell lines (GI50=1-50 nM), with good margin to KDR-driven effects. It also inhibits PDGFR mutants (Tel-PDGFRα, Tel-PDGFRβ, V561D/D842V).
M21825 AZD8329 Others
AZD8329
M25432 NAZ2329 Phosphatase
NAZ2329 is the first cell-permeable inhibitor of R5 subfamily of receptor-type protein tyrosine phosphatases (RPTPs), allosterically and preferentially inhibits PTPRZ (IC50=7.5 µM for hPTPRZ1) and PTPRG (IC50=4.8 µM for hPTPRG) over other PTPs.
M28240 AZD4320  Bcl-2
AZD4320 is a novel BH3-mimicking dual BCL2/BCLxL inhibitor with IC50s of 26 nM, 17 nM, and 170 nM for KPUM-MS3, KPUM-UH1, and STR-428 cells, respectively.



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