About 12 results found for searched term "AZ32" (0.053 seconds)
Cat.No. | Name | Target |
---|---|---|
M1696 | Cediranib | VEGFR/PDGFR |
AZD2171; NSC-732208 | ||
Cediranib (AZD2171) inhibited VEGFR2 and KDR phosphorylation with IC50s of 0.4 and 0.5 nM, respectively. | ||
M5227 | AZD3293 | BACE |
LY3314814 | ||
AZD3293, also known as LY3314814 is an oral beta-secretase 1 cleaving enzyme (BACE) inhibitor. | ||
M5313 | AZD2932 | VEGFR/PDGFR |
AZD2932 is a potent and mutil-targeted protein tyrosine kinase inhibitor with IC50 of 8 nM, 4 nM, 7 nM, and 9 nM for VEGFR-2, PDGFRβ, Flt-3, and c-Kit, respectively. | ||
M5427 | Atazanavir | HIV Protease |
Latazanavir, Zrivada, Reyataz, BMS-232632 | ||
Atazanavir is an azapeptide and HIV-protease inhibitor that is used in the treatment of HIV infections and AIDS in combination with other anti-HIV agents. | ||
M6180 | AZD3264 | IκB/IKK |
AZD3264 is a novel IKK2 inhibitor. | ||
M9411 | AZD-7325 | GABA Receptor |
AZD7325 | ||
AZD-7325 is a GABA-Aα2,3 -selective receptor modulator. | ||
M10158 | AZ32 | ATM/ATR |
AZ-32 | ||
AZ32 is an orally bioavailable and blood-brain barrier-(BBB)penetrating inhibitor of ATM with IC50 of <6.2 nM and 0.31 μM for ATM enzyme in cell. | ||
M10514 | Verdiperstat (AZD3241) | Others |
AZD3241; BHV-3241; CAS#890655-80-8 | ||
Verdiperstat (AZD-3241) is a selective and irreversible inhibitor of myeloperoxidase (MPO) with an IC50 of 630 nM. | ||
M20646 | AZD3229 | c-Kit |
AZD3229 is a potent, pan-KIT mutant inhibitor with potent single digit nM growth inhibition against a diverse panel of mutant KIT driven Ba/F3 cell lines (GI50=1-50 nM), with good margin to KDR-driven effects. It also inhibits PDGFR mutants (Tel-PDGFRα, Tel-PDGFRβ, V561D/D842V). | ||
M21825 | AZD8329 | Others |
AZD8329 | ||
M25432 | NAZ2329 | Phosphatase |
NAZ2329 is the first cell-permeable inhibitor of R5 subfamily of receptor-type protein tyrosine phosphatases (RPTPs), allosterically and preferentially inhibits PTPRZ (IC50=7.5 µM for hPTPRZ1) and PTPRG (IC50=4.8 µM for hPTPRG) over other PTPs. | ||
M28240 | AZD4320 | Bcl-2 |
AZD4320 is a novel BH3-mimicking dual BCL2/BCLxL inhibitor with IC50s of 26 nM, 17 nM, and 170 nM for KPUM-MS3, KPUM-UH1, and STR-428 cells, respectively. |
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