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 About 8 results found for searched term "56-40-6" (0.127 seconds)

Cat.No.  Name Target
M3257 Torsemide Others
Torasemide
Torsemide is a pyridine-sulfonyl urea type loop diuretic with an IC50 of 2.7 ± 0.17 μM.
M9566 Glycine GluR
Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate.
M24893 Mitazalimab TNF Receptor
ADC-1013; JNJ-64457107
Mitazalimab (ADC-1013; JNJ-64457107) is FcγR-dependent CD40 agonist with tumor-directed activity. Mitazalimab activates antigen-presenting cells, e.g. dendritic cells (DC), to initiate tumor-reactive T cells. Therefore, Mitazalimab induces tumor-specific T cells to infiltrate and kill tumors. Mitazalimab remodels the tumor-infiltrating myeloid microenvironment.
M39504 Fmoc-Phe-OH Amino Acid Derivatives
Fmoc-Phe-OH is a phenylalanine derivative.
M25003 Talquetamab Others
JNJ-64407564
Talquetamab (JNJ-64407564) is a potentially first-in-class humanized IgG4ҡ/λ bispecific antibody that binds to GPRC5D (G-protein-coupled receptor family, group C5, member D) and CD3, and induces T-cell-mediated by T-cell recruitment and activation. killing of GPRC5-expressing MM cells through T cell recruitment and activation.Talquetamab (JNJ-64407564) has antitumor activity.
M29016 BPN-15606  Gamma-secretase/Beta-secretase
BPN-15606 is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively. BPN-15606 lowers Aβ42 and Aβ40 levels in the central nervous system of rats and mice. BPN-15606 has acceptable PK/PD properties, including bioavailability, half-life, and clearance.
M30801 KPT-6566  Others
KPT-6566 is a selective and covalent prolyl isomerase PIN1 inhibitor, covalently binds to the catalytic site of PIN1, selectively inhibits and degrades PIN1. KPT-6566 shows an IC50 value of 640 nM and a Ki value of 625.2 nM for PIN1 PPIase domain. KPT-6566 can be used for the research of cancer.
M31065 BPN-15606 besylate  Gamma-secretase/Beta-secretase
BPN-15606 besylate is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively. BPN-15606 besylate lowers Aβ42 and Aβ40 levels in the central nervous system of rats and mice. BPN-15606 besylate has acceptable PK/PD properties, including bioavailability, half-life, and clearance.



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